Medically reviewed by Algery Al Hafi, MSN, APRN, FNP-C
Published May 22, 2026 · Last Updated August 3, 2026
When women hear the word testosterone, they often think of it as a male hormone — something that does not apply to them, or that only matters for muscle and aggression. That misunderstanding has left an enormous number of women with undiagnosed, untreated hormonal deficiencies that affect nearly every dimension of how they feel. Low testosterone in women produces a constellation of symptoms that rarely get attributed to the right cause — because most providers are not looking for it, and most labs do not test it thoroughly. Let me walk you through what I actually see in my patients and what the testing shows.
Why Women Need Testosterone
Testosterone is produced in the ovaries and adrenal glands in women throughout their lives. It peaks in the mid-twenties and declines steadily from there — with a significant additional drop during perimenopause and menopause. Testosterone in women is not an incidental hormone. It is essential for energy metabolism, libido, mood stability, cognitive function, lean muscle maintenance, and bone density.
The reference ranges for “normal” female testosterone are extremely wide — and most conventional labs flag deficiency only at the very bottom of that range. A woman can have testosterone levels that are technically within range but far below what is optimal for her individual biology, and she will feel every bit of that deficit.
The Symptoms That Are Rarely Attributed to Testosterone
Yes, low libido is part of the picture — and it is real, and it deserves to be taken seriously rather than dismissed as a psychological issue. But the symptoms I find most underrecognized are the ones that get attributed to everything else first:
- Persistent fatigue that does not improve with sleep — testosterone directly supports mitochondrial energy production; when it is low, energy at the cellular level suffers
- Loss of motivation and drive — patients describe a flatness, a loss of ambition or competitive edge, a sense of going through the motions
- Difficulty building or maintaining muscle despite consistent exercise — and accelerating loss of muscle tone even without significant lifestyle changes
- Increased central body fat — testosterone helps maintain lean mass and metabolic rate; when it falls, fat accumulation often follows
- Brain fog and word-finding difficulties — cognitive function in women is sensitive to testosterone, not just estrogen
- Mood changes — irritability, anxiety, emotional dysregulation, or a general sense of being flat and unresponsive
How I Test Testosterone in Women
A single total testosterone draw is rarely sufficient. I run total testosterone, free testosterone (the biologically active fraction), and SHBG (sex hormone binding globulin) together. High SHBG — which rises with synthetic estrogen use, thyroid dysfunction, or certain other conditions — can bind testosterone and reduce the free fraction even when total levels appear adequate. You can have “normal” total testosterone and still have insufficient free testosterone available for your tissues to use. The same pattern that causes fatigue often drives the brain fog women associate with perimenopause.
I also run DHEA-S, which is the adrenal precursor to testosterone. Low DHEA-S tells me the building blocks are not available, which requires a different intervention than simply treating low testosterone directly.
What Treatment Looks Like at Aura
For women with confirmed low testosterone, I use compounded testosterone — typically a low-dose topical cream or pellet therapy, depending on the patient’s preference and circumstances. The doses used for women are far lower than what men require, and the titration is careful and individualized. The goal is restoration to a physiologically appropriate level — not supraphysiologic. I monitor levels, symptoms, and response at every follow-up.
The results patients describe are frequently dramatic relative to the subtlety of the intervention. Patients commonly report that energy and motivation return and that the flatness lifts. Individual results may vary.
If these symptoms sound familiar, our hormone optimization program looks at testosterone in the context of your whole hormonal picture.
If you have been told your testosterone is “fine” but you recognize yourself in these symptoms, I want to take a closer look. Book your consultation at Aura Wellness — let’s run the right panel and interpret it in the context of your actual experience.
Compounded Medication Disclosure: Compounded medications are not FDA-approved as finished drug products. They are prepared by state-licensed 503A pharmacies or FDA-registered 503B outsourcing facilities pursuant to an individualized prescription. Compounded preparations have not undergone the same FDA review for safety, efficacy, or quality as commercially manufactured drugs.
